Windows 10 drivers may not be up to date.Windows Firewall may be blocking iTunes from opening.iTunes software may be malfunctioning due to error or bug in iTunes account or iTunes library.Incomplete installation of iTunes or its related software components.Why does iTunes refuse to boot? The following may be the reasons why iTunes is not opening on your Windows 10 computer: The issue gets worse when iTunes not open on Windows 10, stops responding or unexpectedly quits at the middle of backup or file restore.
Fixing unexpected quits and launch issues in iTunes for Windows 10 can be problematic.